The Immunoglobulin D (IgD) Antibody (Rabbit Monoclonal, Clone EP173) from GeneBioSolution is a high-quality antibody optimized for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues). IgD is one of the five classes of human immunoglobulins, expressed on the surface of naïve B cells as a receptor, and plays an essential role in B-cell activation and immune regulation. This antibody provides sensitive and specific membranous and cytoplasmic staining of IgD in B lymphocytes, with minimal background. The EP173 clone is a reliable marker for the identification of IgD-positive B cells, and it is particularly valuable in diagnosing B-cell lymphomas and plasma cell disorders, where subclass restriction may be clinically significant. In pathology, IgD is often used in combination with other immunoglobulin class and light chain antibodies (IgM, IgG, kappa, lambda) to assess clonality and B-cell lineage. In research, IgD antibodies support studies into B-cell development, immune dysregulation, autoimmune diseases, and humoral immunity. All GeneBioSolution antibodies undergo rigorous validation and quality control, ensuring lot-to-lot consistency, reproducible IHC results, and compatibility with both manual and automated staining platforms
Humans; others not tested
Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Buffer with protein carrier and preservative
Store at 2ºC to 8ºC
Pancreatic ductal adenocarcinoma
Cytoplasmic
IgG
Recombinant fragment within Human IMP3
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
