The IgM (Immunoglobulin Mu Heavy Chain) Monoclonal Antibody [Clone IM373] is a mouse-derived monoclonal antibody specifically designed to detect the mu heavy chain of human immunoglobulin M (IgM). IgM is predominantly expressed on immature and naïve B cells and is essential for early humoral immune responses. Clone IM373 offers high specificity and sensitivity in identifying IgM-positive cells in both reactive and neoplastic lymphoid tissues, making it a valuable tool for immunophenotyping in hematopathology.
Mouse
Recombinant heavy chain of human IgM
IM373
IgG1, kappa
Human. Others not known.
293T, Raji or hPBL cells. Tonsil or spleen.
Recognizes a protein of 75kDa, identified as mu heavy chain of human immunoglobulins.
Cytoplasm, Cell Surface and Secreted