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Insulin / IRDN (Beta Cell & Insulinoma Marker)

The Insulin / IRDN Monoclonal Antibody [Clone 2D11-H5 (INS05)] is a mouse monoclonal antibody that specifically detects human insulin, a key peptide hormone synthesized by pancreatic β-cells. This antibody is widely used to identify insulin-expressing cells in both normal and pathological conditions, including pancreatic islets and insulinomas. The clone offers excellent specificity and performance in immunohistochemical assays on formalin-fixed, paraffin-embedded tissues, making it a valuable tool in both diagnostic pathology and diabetes research.

Specifications

Species

Mouse

Immunogen

Purified pig insulin, conjugated to KLH

Clone

2D11-H5 (INS05)

Isotype

IgG1, kappa

Species Reactivity

Human, Cow and Pig. Does not react with Mouse and Rat. Others not known.

Positive Control

MIA PaCa-2 cells or Pancreas.

Specificity

Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through disulfide bonds.

Cellular Localization

Cytoplasmic

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G0161RP