The Insulin / IRDN Monoclonal Antibody [Clone 2D11-H5 (INS05)] is a mouse monoclonal antibody that specifically detects human insulin, a key peptide hormone synthesized by pancreatic β-cells. This antibody is widely used to identify insulin-expressing cells in both normal and pathological conditions, including pancreatic islets and insulinomas. The clone offers excellent specificity and performance in immunohistochemical assays on formalin-fixed, paraffin-embedded tissues, making it a valuable tool in both diagnostic pathology and diabetes research.
Mouse
Purified pig insulin, conjugated to KLH
2D11-H5 (INS05)
IgG1, kappa
Human, Cow and Pig. Does not react with Mouse and Rat. Others not known.
MIA PaCa-2 cells or Pancreas.
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through disulfide bonds.
Cytoplasmic