The Insulin / IRDN Monoclonal Antibody [Clone E2-E3 (INS04)] is a mouse monoclonal antibody designed to detect human insulin, a hormone exclusively produced by pancreatic β-cells. This antibody exhibits strong cytoplasmic staining and is optimized for immunohistochemistry on formalin-fixed, paraffin-embedded tissues. It is ideal for identifying normal pancreatic islets, insulin-producing tumors (insulinomas), and for research focused on diabetes, islet biology, and neuroendocrine tumors.
Mouse
Purified pig insulin, conjugated to KLH
E2-E3 (INS04)
IgG1, kappa
Human, Cow Pig, Rabbit, and Rat. Others not known.
MIA PaCa-2 cells or Pancreas.
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through disulfide bonds.
Cytoplasmic