Fighting Cancer, One Slide at a Time

Insulin / IRDN (Beta Cell & Insulinoma Marker)

The Insulin / IRDN Monoclonal Antibody [Clone E2-E3 (INS04)] is a mouse monoclonal antibody designed to detect human insulin, a hormone exclusively produced by pancreatic β-cells. This antibody exhibits strong cytoplasmic staining and is optimized for immunohistochemistry on formalin-fixed, paraffin-embedded tissues. It is ideal for identifying normal pancreatic islets, insulin-producing tumors (insulinomas), and for research focused on diabetes, islet biology, and neuroendocrine tumors.

Specifications

Species

Mouse

Immunogen

Purified pig insulin, conjugated to KLH

Clone

E2-E3 (INS04)

Isotype

IgG1, kappa

Species Reactivity

Human, Cow Pig, Rabbit, and Rat. Others not known.

Positive Control

MIA PaCa-2 cells or Pancreas.

Specificity

Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through disulfide bonds.

Cellular Localization

Cytoplasmic

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G0162RP