Fighting Cancer, One Slide at a Time

Islet-1 Antibody

The Islet Antibody (Rabbit Monoclonal, Clone EP283) from GeneBioSolution is a high-quality antibody optimized for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues). This antibody detects pancreatic islet cell antigens, making it a valuable tool for identifying and characterizing endocrine cells of the pancreas. The EP283 clone provides sensitive and specific cytoplasmic staining of pancreatic islet cells with minimal background. It is widely used in diagnostic pathology for the evaluation of insulinomas, islet cell hyperplasia, and pancreatic neuroendocrine tumors (PanNETs). By highlighting the endocrine component of the pancreas, it helps differentiate islet-derived tumors from surrounding exocrine tissue. In research, the Islet EP283 antibody is a reliable marker for studies on diabetes mellitus, islet biology, insulin secretion, beta-cell regeneration, and pancreatic endocrinology. It is also applied in investigations of autoimmune diabetes and transplantation studies where islet integrity is critical. All GeneBioSolution antibodies undergo stringent validation and quality control, ensuring lot-to-lot consistency, strong staining performance, and compatibility with both manual and automated IHC systems.

Specifications

Clone Name

GRM468

Specificity

GRM468 reacts to human INI1 (SNF5/SMARCB1). This antibody may also react to mouse or rat INI1, as predicted by immunogen homology.

Immunogen

A peptide corresponding to the C-terminus of human INI1 (SNF5/SMARCB1)

Application

Immunochemistry (IHC) Western Blot (WB)

Species Reactivity

Human

Conjugate

None

Intended Use

Research Use Only

Storage and Stability:

Stable for 1 Year at -20.0°C from date of receipt.

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G1360RP