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Product Overview

Clone: SPM594

Ksp-Cadherin (Kidney-Specific Cadherin), also known as CDH16, is a calcium-dependent cell adhesion molecule from the cadherin family, primarily expressed in the epithelial cells of the kidney, particularly within the distal convoluted tubules and collecting ducts. The SPM594 clone is a mouse monoclonal antibody designed to specifically detect CDH16 in formalin-fixed, paraffin-embedded tissues. Provided as a concentrate, this antibody allows for flexible dilution and optimization based on individual laboratory protocols. Clone SPM594 is widely used in immunohistochemistry for identifying renal epithelial origin in tumors, making it especially valuable in distinguishing renal cell carcinomas from other malignancies. Its strong and specific staining pattern in kidney tissue supports its role as a reliable marker in renal pathology and tumor classification.

Specifications

Species

Mouse

Immunogen

Recombinant human CDH16 protein

Clone

SPM594

Isotype

Mouse / IgG1, kappa

Species Reactivity

Human, Mouse, Rat, Rabbit and Dog. Others not known.

Positive Control

Normal kidney or renal cell carcinoma.

Specificity

This antibody recognizes a protein of 130kDa, identified as Ksp-cadherin.

Cellular Localization

Cell Surface with some cytoplasmic.

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G0469RP