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Product Overview

Clone: CDH16/1071

Ksp-Cadherin (Kidney-Specific Cadherin), also known as CDH16, is a calcium-dependent cell adhesion molecule that belongs to the cadherin superfamily. It is primarily expressed in the epithelial cells of the kidney, particularly in the distal tubules and collecting ducts, playing a crucial role in maintaining epithelial integrity and polarity. The CDH16/1071 clone is a monoclonal antibody specifically developed to detect Ksp-Cadherin in various applications, such as immunohistochemistry (IHC), especially on formalin-fixed, paraffin-embedded tissue sections. As a concentrated reagent, it offers flexibility in dilution and protocol optimization, making it suitable for research and diagnostic purposes involving renal tissue differentiation and tumor classification. Its specificity makes it a valuable tool in distinguishing renal cell carcinomas from other neoplasms.

Specifications

Species

Mouse

Immunogen

Recombinant human CDH16 protein

Clone

CDH16/1071

Isotype

IgG1, kappa

Species Reactivity

Human, Mouse, Rat, Rabbit and Dog. Others not known.

Positive Control

Normal kidney or renal cell carcinoma.

Specificity

This antibody recognizes a protein of 130kDa, identified as Ksp-cadherin.

Cellular Localization

Cell Surface with some cytoplasmic

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G0431RP