Fighting Cancer, One Slide at a Time

talk to us

Genebiosolution > IHC Primary Antibody > LEF1

Product Overview

GR336/Rabbit/Monoclonal

GeneBio's recombinant rabbit antibody recognizes LEF1 (Lymphoid Enhancing Factor 1), a transcription factor that participates as a regulator in Wnt signaling pathways. LEF1 belongs to the TCF/LEF family. LEF1 is an important factor in lymphopoiesis and is expressed normally in T and pro-B cells but not expressed in mature B cells. Strong nuclear expression of LEF1 has been observed in majority of chronic lymphocytic leukemia/small lymphocytic lymphoma cases and LEF1 is not detected in other small B cell lymphomas. Anti-LEF1 may be used as an aid for differentiation of chronic lymphocytic leukemia/small lymphocytic lymphoma from other small B cell lymphomas.

Datasheet Make Enquiry

Specifications

Species Reactivity

Humans; others not tested

Known Applications

Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As

Buffer with protein carrier and preservative

Storage

Store at 2ºC to 8ºC

Control

CLL/SLL

Visualization

Nuclear

Isotype

IgG

Immunogen

Fragment (around aa 100-200) of human LEF1 protein

Ordering Information

Format:

Volume:

Classification
RUO
Catalogue Number
G2642RP

At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.