Product Overview
Clone: SPM282
MAGE-1 (Melanoma Antigen Gene-1) is a cancer-testis antigen that is normally expressed in testicular germ cells but aberrantly expressed in various malignancies, including melanoma, lung, breast, and bladder cancers. It has become an important target in cancer immunotherapy due to its restricted normal tissue expression and strong immunogenicity. The MAGE-1 antibody, Clone SPM282 (Concentrate), is a mouse monoclonal antibody specifically developed to detect MAGE-1 protein in tissue samples. As a concentrated monoclonal reagent, it offers high specificity and affinity for a single epitope, ensuring consistent and reproducible staining results in applications such as immunohistochemistry. Clone SPM282 is particularly useful in research and diagnostic oncology for identifying tumors expressing MAGE-1, contributing to tumor classification, prognosis, and the development of targeted immunotherapeutic strategies.
