Fighting Cancer, One Slide at a Time

Product Overview

Clone: 1014

Major Vault Protein (MVP) is the main structural component of vault ribonucleoprotein particles, which are large cellular organelles implicated in processes such as intracellular transport, signal transduction, and multidrug resistance. The MVP plays a role in cellular defense mechanisms and has been linked to cancer progression and chemoresistance in various tumor types. Clone 1014 (Concentrate) is a mouse monoclonal antibody specifically designed to recognize a single epitope on the MVP protein with high affinity and specificity. Provided as a concentrated formulation, this monoclonal antibody delivers consistent and reproducible results in applications such as immunohistochemistry, Western blotting, and other immunodetection techniques. Clone 1014 is a valuable tool for researchers investigating the biological functions of MVP, its role in disease, and its potential as a biomarker or therapeutic target.

Specifications

Species

Mouse

Immunogen

Proteins precipitated from human breast cancer MCF-7 cells

Clone

1014

Isotype

IgG1, kappa

Species Reactivity

Human. Others not tested.

Positive Control

MCF-7/HeLa cells, breast tumors.

Specificity

Recognizes a protein of 104kDa-110kDa, characterized as major vault protein (MVP).

Cellular Localization

Cytoplasmic

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G0349RP