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RA0352-C.5

Product Overview

Clone: MT1/410

MALT1 (Mucosa-Associated Lymphoid Tissue lymphoma translocation protein 1) is a key signaling molecule involved in the activation of NF-κB and plays a critical role in lymphocyte activation and survival. It is frequently implicated in the pathogenesis of MALT lymphoma, a type of extranodal marginal zone B-cell lymphoma. Clone MT1/410 is a mouse monoclonal antibody developed to specifically recognize the MALT1 protein with high affinity and specificity. This antibody is commonly used in immunohistochemistry and other immunodetection techniques to identify MALT1 expression in tissue samples, aiding in the diagnosis and study of MALT lymphoma and related lymphoproliferative disorders. Clone MT1/410 provides consistent, reproducible results, making it a valuable tool in both research and clinical pathology settings.

Specifications

Species

Mouse

Immunogen

Human MALT1 recombinant fragment (aa 701-808)

Clone

MT1/410

Isotype

IgG1, kappa

Species Reactivity

Human. Others not known.

Positive Control

Jurkat, Daudi, or HeLa cells. Tonsil or lymphoma.

Specificity

Highly expressed in peripheral blood mononuclear cells. Detected at lower levels in bone marrow, thymus and lymph node, and at very low levels in colon and lung.

Cellular Localization

Cytoplasmic

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G0352RP