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Product Overview

Clone: SPM578

MALT1 (Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1) is a key signaling protein involved in the activation of NF-κB and plays a critical role in immune response regulation and lymphocyte activation. It is particularly significant as a biomarker in diagnosing MALT lymphoma, a type of extranodal marginal zone B-cell lymphoma. The Clone SPM578 is a mouse monoclonal antibody provided as a concentrate, specifically developed to detect MALT1 protein expression in formalin-fixed, paraffin-embedded tissue samples. This antibody is widely used in immunohistochemistry to aid in the identification and characterization of MALT lymphoma, helping to differentiate it from other lymphoid malignancies. Its high specificity and sensitivity make it a valuable tool for both research and clinical diagnostic applications in hematopathology.

Specifications

Species

Mouse

Immunogen

Human MALT1 recombinant fragment (aa701-808).

Clone

SPM578

Isotype

IgG1, kappa

Species Reactivity

Reacts with human. Others not known.

Positive Control

Jurkat, Daudi, or HeLa cells. Lymphoma.

Specificity

Recognizes the 93kDa protein, MALT1 (aa701-808).

Cellular Localization

Cytoplasmic.

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G0509RP