Fighting Cancer, One Slide at a Time

Mammaglobin Antibody (Rabbit Monoclonal)

The Mammaglobin Antibody (Rabbit Monoclonal, Clone 31A5) from GeneBioSolution is a high-affinity antibody optimized for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues). Mammaglobin, a glycoprotein belonging to the secretoglobin family, is selectively expressed in normal and neoplastic breast tissue and is widely recognized as a specific biomarker for breast carcinoma. The 31A5 clone provides sensitive and specific cytoplasmic staining of mammaglobin with minimal background, making it a powerful diagnostic marker. It is particularly useful in identifying primary and metastatic breast carcinoma, especially when used as part of an IHC panel including GCDFP-15, ER, PR, and GATA3. Mammaglobin immunostaining is also valuable for distinguishing breast carcinoma metastases from morphologically similar tumors of other origins, supporting pathologists in accurate tumor classification. In research, mammaglobin serves as a marker in studies of breast cancer biology, tumor progression, and potential targeted therapies. All GeneBioSolution antibodies undergo strict validation and quality control, ensuring lot-to-lot consistency, reproducible results, and compatibility with both manual and automated IHC staining systems.

Specifications

Clone Name

GRM140

Specificity

GRM140 reacts to Histone H3 monomethylated at Lysine 4 (K4me1). No cross reactivity with dimethylated Lysine 4 (K4me2), trimethylated Lysine 4 (K4me3), or other methylations in histone H3

Immunogen

A monomethyl-peptide corresponding to Monomethyl-Histone H3 (Lys4)

Application

Western Blot (WB) Chromatin IP (ChIP) Immunocytochemistry (ICC) ELISA Multiplex

Species Reactivity

Human Vertebrates

Conjugate

None

Intended Use

Research Use Only

Storage and Stability:

Stable for 1 Year at -20.0°C from date of receipt.

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G1046RP