A00115-Human-Melanoma-20X-slide-1

Product Overview

Clone: M2-7C10

MART-1 (Melanoma Antigen Recognized by T-cells 1), also known as Melan-A, is a melanocyte differentiation antigen commonly expressed in normal melanocytes and the majority of melanoma cells. It plays an important role in the identification and diagnosis of melanocytic lesions, including malignant melanoma. The Clone M2-7C10 is a mouse monoclonal antibody available as a concentrate, specifically designed for use in immunohistochemistry on formalin-fixed, paraffin-embedded tissues. This antibody provides strong and specific staining of melanocytic cells, making it a reliable marker for distinguishing melanomas from other non-melanocytic tumors. Its application is crucial in diagnostic pathology for confirming melanocytic origin and aiding in the accurate classification of pigmented lesions.

Specifications

Species

Mouse

Clone

M2-7C10

Isotype

Mouse IgG2b, Kappa

Species Reactivity

Human. Clone M2-7C10 does not react with mouse or rat.

Positive Control

Metastatic melanoma in lymph nodes.

Specificity

The clone M2-7C10 MART-1 antibody labels melanomas and other tumors showing melanocyte differentiation.

Immunogen

Recombinant human MART-1 protein was used to generate the MART-1 antibody.

Cellular Localization

Cytoplasmic.

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G00115RP