A00116-Human-Melanoma-20X-slide-1

Product Overview

Clone: M2-9E3

MART-1 (Melanoma Antigen Recognized by T-cells 1), also known as Melan-A, is a melanocyte differentiation antigen consistently expressed in normal melanocytes and the majority of melanomas. It serves as a critical immunohistochemical marker in the diagnosis and classification of melanocytic lesions. The Clone M2-9E3 is a mouse monoclonal antibody provided as a concentrate, specifically developed for use on formalin-fixed, paraffin-embedded tissue sections. This antibody offers strong and specific cytoplasmic staining of melanocytic cells, making it a valuable tool in identifying primary and metastatic melanoma. Its high sensitivity and specificity make it especially useful in differentiating melanocytic tumors from non-melanocytic neoplasms in diagnostic pathology.

Specifications

Species

Mouse

Clone

M2-9E3

Isotype

Mouse IgG2b, Kappa

Species Reactivity

Human, Mouse, Rat.

Positive Control

Metastatic melanoma in lymph nodes.

Specificity

The clone M2-9E2 MART-1 antibody labels melanomas and other tumors showing melanocyte differentiation.

Immunogen

Recombinant human MART-1 protein was used to generate the MART-1 antibody.

Cellular Localization

Cytoplasmic.

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G00116RP