Product Overview
Clone: MUC18/1130
MCAM (Melanoma Cell Adhesion Molecule), also known as MUC18 or CD146, is a transmembrane glycoprotein involved in cell adhesion, signaling, and the regulation of tumor progression and metastasis. It is prominently expressed on the surface of melanoma cells and various other tumor types, playing a key role in cancer cell migration and angiogenesis. The Clone MUC18/1130 is a mouse monoclonal antibody provided as a concentrate, specifically developed for immunohistochemical detection of MCAM/CD146 in formalin-fixed, paraffin-embedded tissues. This antibody produces strong and specific membranous staining, facilitating the identification of melanoma and other MCAM-expressing tumors. Its high sensitivity and specificity make it an important tool for both diagnostic pathology and research applications related to tumor biology and metastasis.
