Product Overview
Clone: MCAM/1101
MCAM (Melanoma Cell Adhesion Molecule), also known as MUC18 or CD146, is a cell surface glycoprotein belonging to the immunoglobulin superfamily that plays a significant role in cell adhesion, migration, and signaling. It is highly expressed in melanoma cells and has been implicated in tumor progression, metastasis, and angiogenesis. The Clone MCAM/1101 is a mouse monoclonal antibody provided as a concentrate, designed for specific detection of MCAM/CD146 in formalin-fixed, paraffin-embedded tissue samples via immunohistochemistry. This antibody exhibits strong and specific membranous staining of melanoma cells and other MCAM-expressing tumors, making it a valuable diagnostic marker for identifying melanoma and assessing tumor aggressiveness. Its application is important in both research and clinical pathology for tumor characterization and prognosis.
