Product Overview
Clone: C146/634
MCAM (Melanoma Cell Adhesion Molecule), also known as MUC18 or CD146, is a cell surface adhesion glycoprotein that plays a vital role in cell-cell interactions, tumor progression, and metastasis, particularly in melanoma and other malignancies. It is involved in processes such as cell migration, angiogenesis, and tumor invasiveness. The Clone C146/634 is a mouse monoclonal antibody supplied as a concentrate, specifically designed for immunohistochemical applications on formalin-fixed, paraffin-embedded tissue samples. This antibody exhibits strong and specific membranous staining of MCAM-expressing cells, making it a valuable marker for the identification and characterization of melanoma and other tumors with elevated MCAM expression. Its use is instrumental in diagnostic pathology and cancer research focused on tumor behavior and metastatic potential.
