Mesothelin

Genebiosolution > Mesothelin

Product Overview

GM25/Monospecific Mouse/Monoclonal

GeneBio’s mouse monoclonal antibody recognizes Mesothelin, a 40kDa glycosyl-phosphatidylinositol-anchored glycoprotein cleaved from a 69kDa precursor protein. Mesothelin immunoreactivity is high in cancers of the ovary (serous papillary, endometrioid and undifferentiated) and pancreas, with less frequent staining seen in adenocarcinomas of the endometrium, lung and stomach/esophagus. Mesothelin is one of the most sensitive markers for mesothelioma.

Datasheet

Specifications

Species Reactivity

Humans; others not tested

Known Applications

Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As

Buffer with protein carrier and preservative

Storage

Store at 2ºC to 8ºC

Control

Mesothelioma

Visualization

Cytoplasmic

Isotype

IgG2b /κ

Immunogen

Recombinant human mesothelin (MSLN) protein fragment (around aa 273-407)

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G2353RP

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