Product Overview
Clone: C5/D5
Microphthalmia Transcription Factor (MITF) is a nuclear transcription factor essential for the development and function of melanocytes, as well as for the regulation of genes involved in melanogenesis, cell cycle progression, and survival. It serves as a highly specific marker for melanocytic differentiation and is widely used in the diagnosis of melanoma, including challenging cases such as amelanotic and metastatic lesions. The Clone C5/D5 is a mouse monoclonal antibody provided as a concentrate, designed for immunohistochemical detection of MITF in formalin-fixed, paraffin-embedded tissue sections. This antibody yields strong nuclear staining in melanocytes and melanoma cells, offering high sensitivity and specificity. Clone C5/D5 is an important diagnostic tool in surgical pathology, aiding in the accurate identification and classification of melanocytic tumors.
