Product Overview

Clone: AE-1

The Mitochondria antibody, Clone AE-1, is a mouse monoclonal antibody designed to detect mitochondrial proteins in human cells, making it a reliable marker for identifying mitochondrial-rich tissues and tumors. Supplied as a concentrate, this antibody is optimized for immunohistochemical applications on formalin-fixed, paraffin-embedded tissue sections. Clone AE-1 produces strong, granular cytoplasmic staining that highlights the abundant mitochondrial content in various cell types. It is particularly useful in distinguishing tumors with high mitochondrial density, such as certain renal cell carcinomas and other neoplasms, as well as in confirming the human origin of cells in xenograft models. This antibody serves as an important tool in both diagnostic pathology and research to aid in tumor characterization and cellular identification.

Specifications

Species

Mouse

Immunogen

Semi-purified mitochondrial preparation

Clone

AE-1

Isotype

IgG1, kappa

Species Reactivity

Human. Does not react with Mouse and Rat. Others not known.

Positive Control

HeLa or HepG2 cells. Hepatic carcinoma.

Specificity

This antibody recognizes a 60kDa antigen associated with the mitochondria in human cells.

Cellular Localization

Mitochondria in cytoplasm

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G0396RP