The MUC2 Antibody (Rabbit Monoclonal, Clone EP187) from GeneBioSolution is a high-performance antibody optimized for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues). Mucin-2 (MUC2) is a secreted gel-forming glycoprotein that constitutes the major component of intestinal mucus, playing a key role in epithelial protection, barrier function, and tumor biology. The EP187 clone provides sensitive and specific cytoplasmic staining of MUC2, with minimal background. It is widely used in diagnostic pathology for identifying mucinous adenocarcinomas, colorectal carcinomas, and goblet cell–rich tumors, supporting tumor classification and differentiation. MUC2 is also an important marker in gastrointestinal pathology, where altered expression patterns are associated with cancer progression, prognosis, and response to therapy. In research, MUC2 antibodies are applied to studies of epithelial differentiation, mucosal immunity, inflammatory bowel disease (IBD), and gastrointestinal cancers, making them valuable in both clinical and translational research. All GeneBioSolution antibodies undergo rigorous validation and quality control, ensuring lot-to-lot consistency, reproducible results, and compatibility with both manual and automated IHC systems.
Humans; others not tested
Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Buffer with protein carrier and preservative
Store at 2ºC to 8ºC
Colon carcinoma
Cell membrane
IgG1 /κ
Synthetic peptide representing a region on the Muc-2 glycoprotein
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
