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Genebiosolution > IHC Primary Antibody > MUC-6

Product Overview

GR437/Rabbit/Monoclonal

GeneBio’s rabbit recombinant monoclonal antibody recognizes MUC-6. The MUC-6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 (MUC-6) expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 (MUC-6) has an altered expression. In normal stomach, Mucin 6 (MUC-6) is associated with Lewis type 2; Mucin 6 (MUC-6) is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 (MUC-6) is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.

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Specifications

Species Reactivity

Humans; others not tested

Known Applications

Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As

Buffer with protein carrier and preservative

Storage

Store at 2ºC to 8ºC

Control

Stomach

Visualization

Cytoplasmic

Isotype

IgG

Immunogen

Recombinant fragment covering tandem repeats of human MUC-6 protein

Ordering Information

Format:

Volume:

Classification
RUO
Catalogue Number
G2793RP

At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.