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MUC1 Antibody (Rabbit Monoclonal)

The MUC-1 Antibody (Rabbit Monoclonal, Clone EP85) from GeneBioSolution is a premium-quality antibody optimized for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues). Mucin-1 (MUC-1) is a high molecular weight transmembrane glycoprotein expressed on the apical surface of most glandular epithelial cells. In normal tissues, MUC-1 plays a protective role in mucosal surfaces, but in carcinomas it is often overexpressed, hypoglycosylated, and abnormally distributed, making it an important tumor marker. The EP85 clone provides sensitive and specific membranous and cytoplasmic staining of MUC-1, with minimal background. It is widely used in diagnostic pathology for detecting breast carcinoma, ovarian carcinoma, pancreatic carcinoma, and other epithelial malignancies. MUC-1 is also a marker of tumor progression, metastasis, and prognosis, making this antibody a valuable tool for clinical decision-making. In addition to diagnostic utility, MUC-1 has significant importance in cancer immunology and targeted therapy research, including as a target for cancer vaccines and monoclonal antibody-based therapeutics. All GeneBioSolution antibodies undergo stringent validation and quality control, ensuring lot-to-lot consistency, reproducible results, and compatibility with both manual and automated IHC systems.

Specifications

Clone Name

GRM150

Specificity

GRM150 reacts to Histone H3 monomethylated at Lysine 9 (K9me1). No cross reactivity with non-modified Lysine 9, dimethylated Lysine 9 (K9me2), trimethylated Lysine 4 (K9me3), or other methylations in histone H3.

Immunogen

A monomethyl-peptide corresponding to Monomethyl-Histone H3 (Lys9).

Application

Western Blot (WB) Chromatin IP (ChIP) Immunocytochemistry (ICC) ELISA Multiplex Immunohistochemistry (IHC)

Species Reactivity

Human Vertebrates

Conjugate

None

Intended Use

Research Use Only

Storage and Stability:

Stable for 1 Year at -20.0°C from date of receipt.

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G1064RP