MUC5AC (Mucin 5AC / Gastric Mucin)

Product Overview

The Mucin 5AC antibody [CLH2] is a mouse monoclonal antibody that specifically recognizes the human MUC5AC protein, a gel-forming mucin primarily expressed in the respiratory and gastric epithelium. This antibody, of the IgG₁ isotype, was developed using a synthetic peptide derived from the tandem repeat region of MUC5AC as the immunogen. It is commonly used in various research applications including immunohistochemistry, immunofluorescence, Western blotting, immunoprecipitation, and flow cytometry, where it aids in detecting and studying MUC5AC expression and distribution in normal and pathological tissues. Due to its specificity, CLH2 is widely used in studies related to mucin biology, particularly in the context of gastrointestinal and respiratory diseases such as gastric cancer, colorectal cancer, asthma, and chronic obstructive pulmonary disease (COPD). The antibody is typically supplied in a liquid format with stabilizing agents and is validated for use on both frozen and formalin-fixed, paraffin-embedded tissue samples.