MUC5AC (Mucin 5AC / Gastric Mucin)

The MUC5AC Mouse Monoclonal Antibody Cocktail [Clones MUC5AC/917 + 45M1] is a powerful dual-clone formulation designed for enhanced detection of Mucin 5AC (MUC5AC), a gel-forming mucin typically expressed by gastric foveolar epithelial cells. This cocktail combines two high-affinity clones for improved sensitivity and epitope coverage, making it ideal for detecting MUC5AC in tissues with variable expression. MUC5AC is commonly used as a marker of gastric-type differentiation and is highly expressed in various mucinous tumors, including those of the lung, stomach, colon, pancreas, and ovary.

Specifications

Species

Mouse

Immunogen

Recombinant human MUC5AC protein (MUC5AC/917); M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient (45M1)

Clone

MTAP/1813

Isotype

MUC5AC/917 + 45M1

Species Reactivity

Human

Positive Control

MCF-7 cells. Human colon or stomach (IHC).

Specificity

Recognizes Mucin 5AC (MUC5AC), a 641kDa glycoprotein belonging to the superfamily of mucins.

Cellular Localization:

Secreted