The MUM1 Antibody (Rabbit Monoclonal, Clone EP190) from GeneBioSolution is a high-quality antibody optimized for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues). MUM1 (Multiple Myeloma Oncogene 1), also known as IRF4, is a transcription factor involved in B-cell differentiation, plasma cell maturation, and immune regulation. The EP190 clone provides sensitive and specific nuclear staining of MUM1, with minimal background. It is a key diagnostic marker in hematopathology, used to identify plasma cell neoplasms, multiple myeloma, diffuse large B-cell lymphoma (DLBCL), and Hodgkin lymphoma. MUM1 is also frequently applied in panels with CD138, BCL6, and CD10 to distinguish germinal center B-cell–like (GCB) vs non-GCB subtypes in lymphoma classification. Beyond diagnostics, MUM1/IRF4 has emerging importance in research on immune regulation, oncogenesis, and transcriptional networks in lymphoid malignancies. Its role in late-stage B-cell differentiation makes it a critical biomarker in both clinical and translational studies. All GeneBioSolution antibodies undergo rigorous validation and quality control, ensuring lot-to-lot consistency, strong nuclear staining, and reproducible results across both manual and automated IHC platforms.
Humans; others not tested
Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Buffer with protein carrier and preservative
Store at 2ºC to 8ºC
Tonsil or myeloma
Nucleus
IgG
Recombinant fragment (corresponding to C-terminal) of IRF4 protein
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
