The MyoD1 Mouse Monoclonal Antibody [Clone MYD712] is a highly specific tool for the detection of MyoD1, a nuclear transcription factor critical for skeletal muscle differentiation. MyoD1 is strongly expressed in rhabdomyosarcomas, especially alveolar and embryonal subtypes, and serves as a reliable marker to distinguish these tumors from other small round blue cell tumors. This antibody is optimized for use in immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues and demonstrates distinct nuclear staining, supporting its use in diagnostic pathology.
Mouse
Recombinant human MyoD1 protein
MYD712
IgG1, kappa
Human. Others not known.
Rhabdomyosarcoma
Recognizes a phosphor-protein of 45kDa, identified as MyoD1.
Nuclear. Only nuclear staining should be considered as evidence of skeletal muscle differentiation.