Fighting Cancer, One Slide at a Time

Myoglobin

Myoglobin is a mouse monoclonal antibody specifically developed to detect myoglobin, a small, oxygen-binding heme protein predominantly expressed in cardiac and skeletal muscle tissues. This antibody targets a well-defined epitope on the myoglobin molecule, allowing for sensitive and specific immunohistochemical identification of muscle-derived cells. Myoglobin plays a key physiological role in oxygen storage and transport within muscle fibers, and its presence is a reliable marker for muscle differentiation. The EP87 clone is widely used in diagnostic pathology to confirm the muscle origin of neoplasms, particularly in distinguishing rhabdomyosarcomas from other small round cell tumors. It is also valuable in forensic and clinical pathology for detecting muscle injury or necrosis, as myoglobin can be released into tissues and fluids following trauma. The antibody provides strong cytoplasmic staining, making it an effective tool for both research and diagnostic applications involving muscle tissue characterization.

Specifications

SPECIES

Rabbit

IMMUNOGEN

Recombinant human full-length Myoglobin (MB) protein

CLONE

EP87

ISOTYPE

IgG / Kappa

FORMAT

This antibody has been pretitered and quality controlled to work on formalin-fixed paraffin-embedded as well as acetone fixed cryostat tissue sections. No further titration is required.

SPECIES REACTIVITY

Human

POSITIVE CONTROL

Skeletal muscle

CELLULAR LOCALIZATION

Cytoplasmic

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G2379RP