Napsin A (Lung Adenocarcinoma Marker)

Napsin A Antibody

The Napsin A Antibody (Rabbit Monoclonal, Clone EP205) from GeneBioSolution is a high-affinity antibody validated for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues). Napsin A is an aspartic proteinase expressed in type II pneumocytes and renal tubules, and it is a well-established biomarker for lung adenocarcinoma and renal cell carcinoma. The EP205 clone provides sensitive and specific cytoplasmic and granular staining of Napsin A, with minimal background. It is widely used in diagnostic pathology as a lung adenocarcinoma marker, helping distinguish primary lung adenocarcinoma from squamous cell carcinoma and metastatic tumors. In clinical practice, it is commonly employed alongside TTF-1 to improve diagnostic accuracy in non-small cell lung cancer (NSCLC) subtyping. Napsin A is also a useful adjunct marker in renal cell carcinoma diagnosis, where its expression helps confirm renal origin in metastatic tumors. In research, Napsin A antibodies are applied in studies of lung biology, carcinogenesis, and therapeutic development. All GeneBioSolution antibodies undergo strict validation and quality control, ensuring lot-to-lot consistency, strong staining performance, and reproducible results on both manual and automated IHC platforms. Clinical & Research Applications Diagnostic marker for lung adenocarcinoma (in combination with TTF-1) Differentiation of lung adenocarcinoma vs squamous carcinoma and metastases Adjunct marker for renal cell carcinoma and renal origin tumors Research into lung carcinogenesis, NSCLC subtyping, and targeted therapies