Fighting Cancer, One Slide at a Time

Nestin Antibody

The Nestin Antibody (Mouse Monoclonal, Clone 10C2) from GeneBioSolution is a high-quality antibody validated for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues). Nestin is a class VI intermediate filament protein expressed in neural stem cells, progenitor cells, and certain tumors, playing a key role in neurogenesis, development, and cellular plasticity. The 10C2 clone provides sensitive and specific cytoplasmic staining of nestin with minimal background. In pathology, Nestin is an established marker for gliomas, neuroblastomas, and other central nervous system tumors, supporting diagnosis and tumor grading. It is also used in identifying angiogenesis, as nestin is expressed in proliferating endothelial cells during neovascularization. In research, Nestin is widely applied in studies of stem cell biology, neural regeneration, and tissue development, serving as a marker of multipotent progenitor cells across multiple tissues, including the nervous system, pancreas, and muscle. All GeneBioSolution antibodies undergo stringent validation and quality control, ensuring lot-to-lot consistency, reproducible staining, and compatibility with both manual and automated IHC systems.

Specifications

Antibody Type

Mouse Monoclonals

Host

Mouse

Applications

Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot

Species Reactivity

Human

Research Areas

Dendritic Cell Marker

Isotype / Light Chain

IgG1 / Kappa

Cellular Localization

Secreted

Gene Name

NAPSA

Positive Control

Lung adenocarcinoma.

Immunogen

Recombinant human Napsin-A protein fragment (aa189-299) (exact sequence is proprietary)

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G9476RP