The Nestin Antibody (Mouse Monoclonal, Clone 10C2) from GeneBioSolution is a high-quality antibody validated for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues). Nestin is a class VI intermediate filament protein expressed in neural stem cells, progenitor cells, and certain tumors, playing a key role in neurogenesis, development, and cellular plasticity. The 10C2 clone provides sensitive and specific cytoplasmic staining of nestin with minimal background. In pathology, Nestin is an established marker for gliomas, neuroblastomas, and other central nervous system tumors, supporting diagnosis and tumor grading. It is also used in identifying angiogenesis, as nestin is expressed in proliferating endothelial cells during neovascularization. In research, Nestin is widely applied in studies of stem cell biology, neural regeneration, and tissue development, serving as a marker of multipotent progenitor cells across multiple tissues, including the nervous system, pancreas, and muscle. All GeneBioSolution antibodies undergo stringent validation and quality control, ensuring lot-to-lot consistency, reproducible staining, and compatibility with both manual and automated IHC systems.
Mouse Monoclonals
Mouse
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
Human
Dendritic Cell Marker
IgG1 / Kappa
Secreted
NAPSA
Lung adenocarcinoma.
Recombinant human Napsin-A protein fragment (aa189-299) (exact sequence is proprietary)