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Genebiosolution > IHC Primary Antibody > Non-phospho (Active)β-Catenin -S33/S37/T41 Rabbit mAb

Product Overview

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.

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Specifications

Source

Rabbit

Isotype

IgG

Purification

Affinity purification

Storage

Store at -20℃. Avoid freeze / thaw cycles

Observed MW

92kDa/92kd

Calculated MW

85kDa

Applications

WB,IHC-P,ELISA

Cross-Reactivity

Human,Mouse,Rat

Clone number

GR53641

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Non-phospho (Active)β-Catenin -S33/S37/T41 (NP_001895.1).

Synonyms

EVR7; CTNNB; MRD19; NEDSDV; armadillo; Non-phospho (Active)β-Catenin -S33/S37/T41

Ordering Information

Format:

Volume:

Classification
RUO
Catalogue Number
G22180RP

At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.