The Oct-2 Antibody from GeneBioSolution is a high-quality antibody validated for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues). Oct-2 (Octamer-binding transcription factor 2, also known as POU2F2) is a transcription factor essential for B-cell differentiation, immunoglobulin gene regulation, and plasma cell development. This antibody provides sensitive and specific nuclear staining of Oct-2 in B lymphocytes and plasma cells, with minimal background. It is a critical marker in hematopathology, particularly in the classification of B-cell non-Hodgkin lymphomas, multiple myeloma, and other plasma cell neoplasms. Oct-2 immunostaining is commonly combined with BOB.1 and PAX5 to provide a comprehensive assessment of B-cell lineage and differentiation status. In research, Oct-2 is a valuable tool for investigating B-cell biology, transcriptional regulation, immunoglobulin gene activation, and immune disorders, making it important for both diagnostic and translational studies. All GeneBioSolution antibodies undergo rigorous validation and quality control, ensuring lot-to-lot consistency, strong nuclear staining, and reproducible results across manual and automated IHC systems.
Humans; others not tested
Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Buffer with protein carrier and preservative
Store at 2ºC to 8ºC
B-cell lymphoma
Nuclear
IgG
Recombinant human OCT2 protein fragment (around aa 112-297)
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
