The OCT-4 Antibody from GeneBioSolution is a premium-quality antibody optimized for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues). OCT-4 (Octamer-binding transcription factor 4, also known as POU5F1) is a transcription factor and master regulator of pluripotency and stem cell self-renewal. It plays a central role in maintaining the undifferentiated state of embryonic stem cells and is widely studied in stem cell biology, regenerative medicine, and oncology. This antibody provides sensitive and specific nuclear staining of OCT-4, with minimal background. It is a key diagnostic marker in pathology for identifying germ cell tumors, including seminomas, embryonal carcinomas, and dysgerminomas, where OCT-4 expression confirms stem-like tumor properties. Beyond its diagnostic value, OCT-4 is indispensable in research on stem cell reprogramming, induced pluripotent stem cells (iPSCs), and cellular differentiation pathways. Detecting OCT-4 helps researchers evaluate pluripotency status, transcriptional regulation, and tumorigenic potential of stem-like cells. All GeneBioSolution antibodies undergo rigorous validation and quality control, ensuring lot-to-lot consistency, reproducible IHC results, and compatibility with both manual and automated staining systems.
Humans; others not tested
Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Buffer with protein carrier and preservative
Store at 2ºC to 8ºC
Seminoma
Nuclear
IgG
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
