Product Overview
Clone: ODC1/485
Ornithine Decarboxylase-1 (ODC-1), Clone ODC1/485, is a monoclonal antibody designed to detect ornithine decarboxylase-1, a key rate-limiting enzyme involved in polyamine biosynthesis. ODC-1 catalyzes the decarboxylation of ornithine to putrescine, which is essential for cell growth, differentiation, and proliferation. This enzyme is often upregulated in rapidly dividing cells and has been implicated in the pathogenesis of various cancers. Clone ODC1/485 provides specific cytoplasmic staining in cells expressing ODC-1 and is optimized for immunohistochemical analysis of formalin-fixed, paraffin-embedded tissue sections. It is widely used in research and diagnostic pathology to study cell proliferation, tumor biology, and to evaluate the expression of ODC-1 as a potential biomarker in malignancies. The high specificity and consistent performance of Clone ODC1/485 make it a valuable tool for investigating polyamine metabolism in normal and diseased tissues.
