The PAR2 Rabbit Monoclonal Antibody is a highly specific and sensitive reagent for detecting Protease-Activated Receptor 2 (PAR2, also known as F2RL1), a G-protein coupled receptor implicated in signal transduction, inflammation, tumor progression, and pain pathways. PAR2 is activated by serine proteases such as trypsin and tryptase, playing a central role in immune regulation, vascular biology, and cancer biology. This antibody provides sharp, reproducible results in immunohistochemistry (IHC), western blotting (WB), immunofluorescence (IF), and ELISA, making it a valuable tool for both research and diagnostic studies. In oncology and pathology, PAR2 expression has been linked to tumor growth, angiogenesis, and metastasis in cancers including breast, colon, pancreatic, and prostate carcinoma. It is also widely studied in inflammatory diseases, arthritis, asthma, and gastrointestinal disorders, where aberrant PAR2 activation contributes to chronic inflammation and tissue remodeling. The PAR2 Rabbit Monoclonal Antibody offers superior epitope recognition and binding affinity compared to conventional mouse antibodies, ensuring high sensitivity, low background staining, and consistent batch-to-batch performance.
Rabbit
IgG
Affinity purification
Store at -20℃. Avoid freeze / thaw cycles
55kDa
44kDa
SMab Recombinant Monoclonal Antibody
WB,IHC-P,ELISA
Human,Mouse,Rat
GR1246
A synthetic peptide corresponding to a sequence within amino acids 298-397 of human PAR2 (P55085).
PAR2; GPR11