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PAR2 Antibody

The PAR2 Rabbit Monoclonal Antibody is a highly specific and sensitive reagent for detecting Protease-Activated Receptor 2 (PAR2, also known as F2RL1), a G-protein coupled receptor implicated in signal transduction, inflammation, tumor progression, and pain pathways. PAR2 is activated by serine proteases such as trypsin and tryptase, playing a central role in immune regulation, vascular biology, and cancer biology. This antibody provides sharp, reproducible results in immunohistochemistry (IHC), western blotting (WB), immunofluorescence (IF), and ELISA, making it a valuable tool for both research and diagnostic studies. In oncology and pathology, PAR2 expression has been linked to tumor growth, angiogenesis, and metastasis in cancers including breast, colon, pancreatic, and prostate carcinoma. It is also widely studied in inflammatory diseases, arthritis, asthma, and gastrointestinal disorders, where aberrant PAR2 activation contributes to chronic inflammation and tissue remodeling. The PAR2 Rabbit Monoclonal Antibody offers superior epitope recognition and binding affinity compared to conventional mouse antibodies, ensuring high sensitivity, low background staining, and consistent batch-to-batch performance.

Specifications

Source

Rabbit

Isotype

IgG

Purification

Affinity purification

Storage

Store at -20℃. Avoid freeze / thaw cycles

Observed MW

55kDa

Calculated MW

44kDa

Category

SMab Recombinant Monoclonal Antibody

Applications

WB,IHC-P,ELISA

Cross-Reactivity

Human,Mouse,Rat

Clone number

GR1246

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 298-397 of human PAR2 (P55085).

Synonyms

PAR2; GPR11

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G5103RP