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Parathyroid hormone (PTH) Antibody

The Parathyroid Hormone (PTH) Antibody is a highly specific and sensitive reagent for the detection of parathyroid hormone, a key regulator of calcium and phosphate homeostasis. PTH, secreted by the parathyroid glands, plays a central role in maintaining bone metabolism, renal calcium reabsorption, and vitamin D activation. This antibody provides strong and reproducible results in immunohistochemistry (IHC), immunofluorescence (IF), western blotting (WB), and ELISA, making it a valuable tool for both diagnostic pathology and endocrine research. Clinically, the PTH antibody is widely used to identify parathyroid adenomas, hyperplasia, and carcinomas, and to differentiate parathyroid tissue from adjacent thyroid or lymphoid structures. It is also useful in studying parathyroid-related disorders, such as primary and secondary hyperparathyroidism, osteoporosis, and metabolic bone diseases. In research applications, the antibody helps investigate endocrine regulation, calcium signaling pathways, and bone remodeling mechanisms. The PTH Antibody is validated for use on formalin-fixed paraffin-embedded (FFPE) tissue samples and optimized with heat-induced epitope retrieval (HIER) protocols, ensuring clear and specific cytoplasmic staining of parathyroid cells. Its high affinity and low background performance provide consistent and reliable results across both manual and automated staining platforms. Available in multiple vial sizes and supplied in concentrated or ready-to-use formulations, each lot undergoes rigorous quality control testing to guarantee reproducibility and diagnostic accuracy. With its superior sensitivity and clinical relevance, the Parathyroid Hormone (PTH) Antibody is an essential tool for pathologists, endocrinologists, and biomedical researchers focused on parathyroid biology, calcium regulation, and endocrine pathology.

Specifications

Species Reactivity

Humans; others not tested

Known Applications

Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As

Buffer with protein carrier and preservative

Storage

Store at 2ºC to 8ºC

Control

Parathyroid

Visualization

Cytoplasmic

Isotype

IgG2b /κ

Immunogen

A synthetic peptide around aa 1-34 of human mature-PTH-polypeptide; A recombinant fragment around aa 32-115 of human mature PTH-polypeptide (exact sequence is proprietary)

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G2378RP