Prostate Specific Antigen (PSA)

Genebiosolution > Prostate Specific Antigen (PSA)

Product Overview

Clone: KLK3/801

PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia.

Datasheet

Specifications

Species

Mouse

Immunogen

Recombinant human KLK3 protein

Clone

KLK3/801

Isotype

IgG1, kappa

Species Reactivity

Human. Others not known.

Positive Control

PC12 cells or normal prostate or prostate carcinoma.

Specificity

Recognizes a single protein of 33-34kDa, identified as the prostate specific antigen (PSA). This monoclonal antibody is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues.

Cellular Localization

Cytoplasmic

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G0009RP

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