This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.
Rabbit
IgG
Affinity purification
Store at -20℃. Avoid freeze / thaw cycles
38kDa
31kDa
SMab Recombinant Monoclonal Antibody
WB,IHC-P,IF/ICC,ELISA,FC (intra)
Human,Rat
GR63111
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PU.1/SPI1 (NP_003111.2)
OF; PU.1; AGM10; SFPI1; SPI-1; SPI-A; PU.1/SPI1