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Product Overview

Clone: C3e/3125R

Recombinant CD3ε (T-Cell Marker), Clone C3e/3125R, is a monoclonal antibody specifically engineered to detect the CD3 epsilon (CD3ε) chain, an essential component of the T-cell receptor (TCR) complex expressed on the surface of mature T lymphocytes. CD3ε plays a critical role in T-cell activation, signal transduction, and immune response regulation. Clone C3e/3125R provides strong and specific membranous staining of T cells and is optimized for immunohistochemical analysis on formalin-fixed, paraffin-embedded tissue sections. This antibody is widely used in diagnostic pathology to identify and characterize T-cell populations in lymphoid tissues and tumors, including T-cell lymphomas and leukemias. Its high specificity and reliable staining pattern make Clone C3e/3125R a valuable tool in both clinical diagnostics and immunological research focused on T-cell biology and immune-mediated diseases.

Specifications

Species

Rabbit

Immunogen

Recombinant human CD3e fragment (around aa 23-119) (exact sequence is proprietary)

Clone

C3e/3125R

Isotype

IgG / Kappa

Species Reactivity

Human

Positive Control

Jurkat and MOLT-4 cells. Human tonsil or lymph node.

Specificity

Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa.

Cellular Localization

Cell membrane

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G0659RP