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Genebiosolution > IHC Primary Antibody > ROS1

Product Overview

GR400/Rabbit/Monoclonal

The ROS1,GR400 is a rabbit monoclonal antibody designed to specifically detect the ROS1 protein, a receptor tyrosine kinase involved in cell growth and differentiation. ROS1 rearrangements and mutations are implicated in various cancers, most notably non-small cell lung carcinoma (NSCLC), where they serve as important therapeutic targets. This monoclonal antibody, derived from rabbit sources, offers high specificity and sensitivity for ROS1 detection in research and clinical applications such as immunohistochemistry and Western blotting. The ZR400 clone provides reliable identification of ROS1 expression and fusion proteins, aiding in the diagnosis, prognosis, and treatment decision-making processes in oncology. Its use is critical for identifying patients who may benefit from targeted therapies against ROS1-driven tumors.

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Specifications

Species Reactivity

Humans; others not tested

Known Applications

Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As

Buffer with protein carrier and preservative

Storage

Store at 2ºC to 8ºC

Control

Human brain, lung adenocarcinoma or primary glioblastoma

Visualization

Cell surface

Isotype

IgG

Immunogen

Recombinant fragment corresponding to the cytoplasmic domain of human ROS1 protein

Ordering Information

Format:

Volume:

Classification
RUO
Catalogue Number
G2756RP

At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.