This antibody is useful for studying the distribution and level of both free and bound Secretory Component. Secretory Component is differentially expressed in epithelium, and the antibody is a popular marker for identifying subpopulations of epithelial cells and epithelial differentiation. The Secretory Component antibody is a useful research tool for studying mucosal immunity, inflammation, remodeling, differentiation and tumorigenesis, all processes associated with differential Secretory Component expression.
Mouse
Recombinant human ECM1 protein
ECM1/792
IgG1, kappa
Human and Rat. Others not known.
Stomach, lung, or breast tumor.
This antibody reacts with a reduction-resistant epitope present in both free and SIgA bound Secretory Component. It does not react with the cell lines lacking Secretory Component.
Cell surface and cytoplasmic