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Product Overview

This antibody is useful for studying the distribution and level of both free and bound Secretory Component. Secretory Component is differentially expressed in epithelium, and the antibody is a popular marker for identifying subpopulations of epithelial cells and epithelial differentiation. The Secretory Component antibody is a useful research tool for studying mucosal immunity, inflammation, remodeling, differentiation and tumorigenesis, all processes associated with differential Secretory Component expression.

Specifications

Species

Mouse

Immunogen

Recombinant human ECM1 protein

Clone

ECM1/792

Isotype

IgG1, kappa

Species Reactivity

Human and Rat. Others not known.

Positive Control

Stomach, lung, or breast tumor.

Specificity

This antibody reacts with a reduction-resistant epitope present in both free and SIgA bound Secretory Component. It does not react with the cell lines lacking Secretory Component.

Cellular Localization

Cell surface and cytoplasmic

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G0106RP