Genebiosolution > IHC Primary Antibody > Smooth Muscle Myosin Heavy Chain (SM-MHC) (Leiomyosarcoma & Myoepithelial Cell Marker)

Product Overview

Clone: SMMS-1

Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2.

Specifications

Species

Mouse

Immunogen

Human uterus extract

Clone

SMMS-1

Isotype

IgG1, kappa

Species Reactivity

Human, Cow, Pig, Dog, Cat, Rabbit, Rat, Guinea pig and Chicken. Others not known.

Positive Control

Uterus or normal breast.

Specificity

This antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.

Cellular Localization

Cytoplasmic