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Product Overview

GM171/Monospecific Mouse/Monoclonal

GeneBio’s mouse monoclonal recombinant antibody recognizes SOX-9. SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. SOX9 plays an important role in the normal skeletal development. It may regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes.

Specifications

Species Reactivity

Humans; others not tested

Known Applications

Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As

Buffer with protein carrier and preservative

Storage

Store at 2ºC to 8ºC

Control

Human pancreas

Visualization

Nuclear

Isotype

IgG1 /κ

Immunogen

Recombinant human SOX9 protein fragment (around aa393-508)

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G2483RP