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Genebiosolution > IHC Primary Antibody > Synaptophysin

Product Overview

GR445/Rabbit/Monoclonal

GeneBio’s rabbit recombinant antibody recognizes Synaptophysin, an N-glycosylated integral membrane protein found in neurons and endocrine cells. Synaptophysin contains four transmembrane domains and may function as a gap junction-like channel. GeneBio’s recombinant Synaptophysin antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular, cytoplasmic staining is observed, which correlates with the distribution of the antigen within neurosecretory vesicles. Synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.

Synaptophysin is a protein that can be demonstrated in a range of neural and neuroendocrine tissues using IHC. Synaptophysin is a specific marker for these tissues and can be used to identify tumors arising form them. Pathologists often perform IHC to help identify synaptophysin-producing cells in tissue samples.

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Specifications

Species Reactivity

Humans; others not tested

Known Applications

Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As

Buffer with protein carrier and preservative

Storage

Store at 2ºC to 8ºC

Control

Pancreas

Visualization

Cytoplasmic

Isotype

IgG

Immunogen

Recombinant fragment (around aa 224-313) of human Synaptophysin (SYP) protein

Ordering Information

Format:

Volume:

Classification
RUO
Catalogue Number
G2801RP

At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.