Synaptophysin (SYP, also known as major synaptic vesicle protein p38) is a 38-kDa integral membrane glycoprotein that regulates synaptic vesicle endocytosis. It is the most abundant synaptic vesicle protein by mass. Synaptophysin is present in neuroendocrine cells and neurons that participate in synaptic transmission. Synaptophysin is a useful marker for the identification of neuroendocrine cells and neoplasms. Synaptic proteins including synaptophysin are reduced in brain tissue from patients with Alzheimer's disease.(PMID: 3010302; 21658579)
Rabbit
IgG
Affinity purification
Store at -20℃. Avoid freeze / thaw cycles
38kDa/37kDa
34kDa
SMab Recombinant Monoclonal Antibody
WB,IHC-P,IF/ICC,IP,ELISA
Human,Mouse,Rat
Recombinant fusion protein containing a sequence corresponding to amino acids 224-313 of human Synaptophysin (NP_003170.1).
SYP; SYN; MRX96