TAG-72 (Tumor-Associated Glycoprotein), Clone CA72/733 (Concentrate), is a mouse monoclonal antibody that specifically targets TAG-72, a tumor-associated glycoprotein complex commonly expressed on the surface of various adenocarcinomas, including those originating in the colon, stomach, pancreas, ovary, and breast. The CA72/733 clone is highly specific for a sialylated epitope present on TAG-72, which is largely absent in normal adult tissues, making it a valuable biomarker for cancer diagnosis and differentiation. Supplied in a concentrated format, this antibody allows for flexible optimization in immunohistochemistry (IHC), enabling precise staining protocols tailored to individual laboratory needs. It is particularly useful in distinguishing malignant adenocarcinomas from benign tissues and other tumor types, especially in metastatic or poorly differentiated cases. The CA72/733 antibody is widely used in both clinical pathology and research settings to support cancer detection, classification, and the study of tumor progression and metastasis.
Mouse
Recombinant human TAG-72 protein
CA72/733
IgG1, kappa
Human, Cow, Dog, and Rat. Others not known.
Jurkat cells, breast or lung carcinoma.
Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This antibody defines the mucin-carried sialylated-Tn epitope.
Cytoplasmic and cell surface
