This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants.
Rabbit
IgG
Affinity purification
Store at -20℃. Avoid freeze / thaw cycles
70kDa
62kDa
SMab Recombinant Monoclonal Antibody
WB,IHC-P,ELISA
Human,Mouse,Rat
GR1829
Recombinant fusion protein containing a sequence corresponding to amino acids 191-440 of human TFE3 (P19532).
TFEA; RCCP2; RCCX1; MRXSPF; bHLHe33; TFE3
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
