The Anti-Thymidine Phosphorylase / PD-ECGF Antibody [Clone P-GF.44C] is a mouse monoclonal antibody specifically designed to detect Thymidine Phosphorylase (TP), also known as Platelet-Derived Endothelial Cell Growth Factor (PD-ECGF), a well-known marker of angiogenesis. TP is overexpressed in a variety of tumors and plays a significant role in tumor growth, invasion, and metastasis through its ability to promote new blood vessel formation. This antibody is validated for use in immunohistochemistry on formalin-fixed, paraffin-embedded (FFPE) tissue sections, making it an essential tool for cancer research and pathology applications.
Mouse
Recombinant full-length human Thymidine Phosphorylase (TP / PD-ECGF) protein.
P-GF.44C.
IgG1
Reacts with human, mouse, and rat. Others not known.
HUVEC cells. Breast, bladder, lung or Kaposi Tumors.
Recognizes a protein (amino acid 482) of 55kDa (in vivo 110kDa homodimer), identified as platelet-derived endothelial growth factor (PD-ECGF), same as thymidine phosphorylase (TP) or gliostatin.
Cytoplasmic and Nuclear.