The TLE1 monoclonal antibody [CloneGM93] is a highly specific mouse monoclonal antibody designed to detect TLE1, a transcriptional corepressor involved in Wnt/β-catenin and Notch signaling pathways. TLE1 expression is notably upregulated in synovial sarcoma, making it a valuable immunohistochemical marker for the diagnosis of this tumor subtype. This monospecific antibody ensures high signal clarity with minimal background and is validated for use in formalin-fixed, paraffin-embedded (FFPE) tissue sections.
Humans; others not tested
Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Buffer with protein carrier and preservative
Store at 2ºC to 8ºC
Synovial sarcoma
Cytoplasmic
IgG2a /κ
Recombinant human TLE1 fragment (aa 175-338)